ANGUS has completed commercial production of its HEPES buffer products

Time:2023-01-09

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Buffalo, IL, USA -ANGUS Chemical Company ("ANGUS"), a leading global producer of specialty chemicals focused on the life sciences and industrial markets, today announced that it has completed commercial production of its HEPES buffer products at its facility in Stirlington, Louisiana.

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HEPES is a multi-purpose biological buffer that is often used to maintain physiological pH and an ideal environment for cell growth. HEPES is widely used in bioprocess and diagnostic markets such as cell culture, tissue culture, protein purification, cell lysis, immunoprecipitation and live cell imaging. HEPES buffers (international cosmetic raw material name: hydroxyethyl piperazine ethanesulfonic acid) can also be used in combination with other raw materials to support the quality and performance of skin care and cosmetics.

HEPES Biologics Plus grade buffers are manufactured at ANGUS 'facility in Stirlington and comply with ANGUS' uniform global quality management system, including ISO 9001:2015 certified production process monitoring and plant control systems. The comprehensive test program uses validated assay methods including endotoxins, microbial loadings, DNase, RNase, protease, and yeast/mold to support customer validation.

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"Our recent investment in new capacity significantly expands our portfolio of homegrown biobuffers and positions ANGUS to become the world's leading supplier of HEPES molecules." Laura Kaepplinger, Global Strategy Director, ANGUS Life Sciences, said, "ANGUS is committed to supply chain security and continuity to address the rapidly growing demand for critical life sciences chemicals, including HEPES, TRIS aminometriol, and TRIS-HCL trimethylol aminomethylene hydrochloride."

"The commercial production of HEPES is a natural fit with our strategy to be the world's most transparent and reliable producer of key upstream and downstream chemicals for bioprocesses," David Neuberger, ANGUS President and Chief Executive Officer, said: "Our continued investment in ANGUS 'world-class plants, processes and systems is central to this strategy. The investment will allow us to expand our production capacity and expand our product line to meet the quality, purity and regulatory requirements of the global life sciences market.


About us

About ANGUS

ANGUS is a leading global producer of specialty chemicals for the biotechnology, pharmaceutical, consumer and industrial markets. ANGUS produces its unique nitroalkane derivatives, including its flagship AMP™ (aminomethylpropanol) additive and TRIS AMINO™ (aminotriol) buffer, through a fully synthetic process at ISO 9001-compliant facilities in the United States and Germany. ANGUS serves its global customers through six regional customer service centers in Chicago, USA; Paris, France; Sao Paulo, Brazil; Singapore; Shanghai, China; and Mumbai, India. The company is headquartered in Buffalo, Illinois, USA. Details are available at www.angus.com.

About Yalu Chemical Trading (Shanghai) Co., LTD

Yalu Chemical Trading (Shanghai) Co., Ltd. is ANGUS Chemical Company's subsidiary in China, responsible for ANGUS products in Greater China sales and after-sales support. The company is located at Room 1001, Block A1, No. 200, Tianlin Road, Xuhui District, Shanghai. The company has two warehouses in Shanghai and Dongguan respectively. For more sales and product information, please contact apr_cc@angus.com or call 021-5389 3333.



Warmly celebrate Bailu Biological as an authorized distributor of Angus Chemical

Warm celebration

In January 2022, we joined hands with Angus, the world-renowned manufacturer of TRIS AMINO® (triamine) buffer, and officially became its authorized agent in South China to jointly serve the Chinese market. Bailu Biological has been providing you with high quality products, high quality technical services, so that you can choose and use buffers without wohhy.

ANGUS Chemical Company (" Angus ") is a specialty and fine chemicals company that develops new chemical products to help customers achieve better product and process performance. Angus strives to continuously improve its products and services by mastering science and technology. The company's unique innovations in nitroalkane chemical reactions create complex molecules with a wide range of applications. The inherent properties of this chemical process produce multifunctional additives that can help improve performance, reduce reaction steps and reduce synthesis costs.

Angus is the world's only fully synthetic producer of TRIS AMINO® (aminotriol) buffers. The products comply with regulatory requirements around the world, so they are widely used in the global pharmaceutical and biotechnology fields. With more than 50 years of experience in the production of trimethamine, they continue to provide the booming global market with TRIS AMINO® products at the required grade, ensuring the best functionality and compliance.

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Strictly control the production process to ensure product quality and performance

By synthesizing TRIS (TRIS) in the vapor phase, Angerstone not only reduces the use of highly toxic chemicals, but also avoids the possibility of toxic impurities in tris, which is difficult for any supplier to do. This special process not only allows Angus to produce pharmaceutical grade products, but also enables us to control every step of the production process, leaving the entire production line in Louisiana, USA, and Ibn Babylon, Germany - from production equipment, pipes, intermediates, and even basic raw materials - under strict control.

Angus production lines in Louisiana, USA, and Ibn Babylon, Germany, as well as Angus Life Sciences warehouses and packaging lines in Niagara Falls, NY, USA, are cGMP compliant and ISO 9001:2008 quality system certified.


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Product supervision

Angus encourages customers to monitor the application of Angus products from a human health and environmental quality perspective. To ensure that Angus products are not used for unintended purposes, all Angus employees assist customers with environmental and product safety issues. If you have questions for advice and assistance, or require product safety data sheets and other information, please contact the appropriate Angus representative at the number provided in this document.

®™ ANGUS CHEMICAL COMPANY trademark

Note: Patents owned by Angus or others may not be infringed arbitrarily. As conditions of use and applicable laws may vary from time to time and place to place, it is up to Customer to determine whether the products and information in this document are appropriate for Customer's intended use, and it is up to Customer to ensure that its workplace and product handling practices comply with applicable laws and other governmental decrees. The products shown in this material may not be available for sale and/or may not be available for sale in all locations of Angus and the claims made may not be recognized in all countries. Angus assumes no responsibility or liability for the information contained in this document. Except where specifically stated, references to "ANGUS CHEMICAL COMPANY", "Angus" or "the Company" refer to the Angus Chemical Company legal entity that sells products to customers. No wahhanties are made in this document: All implied wahhanties of merchantability or fitness for a particular purpose of application are expressly excluded.

Conclusion

Guangzhou Bailu Biological will join hands with Angus Chemical to bring high-quality buffers to the biopharmaceutical industry, and jointly help the vigorous development of China's biopharmaceutical industry!